2021 (from Jan. to Dec.)

【論文】

  1. Nakanishi T, Nakamura Y, Umeno J., Recent advances in studies of SLCO2A1 as a key regulator of the delivery of prostaglandins to their sites of action, Pharmacol Ther, 223:107803, 2021, doi: 10.1016/j.pharmthera.2021.107803(総説)

  2. ​Saveleva EE, Tyutrina ES, Nakanishi T, Tamai I, Salmina AB., The inhibitors of the apical sodium-dependent bile acid transporter (ASBT) as promising drugs, Biochem Mosc Suppl B Biomed Chem, 15:16-26, 2021, doi: 10.1134/S1990750821010078(総説)

  3. Kobayashi M, Mizutani A, Okamoto T, Muranaka Y, Nishi K, Nishii R, Shikano N, Nakanishi T, Tamai I, Kleinerman ES, Kawai K., Assessment of drug transporters involved in the urinary secretion of [99mTc]dimercaptosuccinic acid. Nucl Med Biol. 94-95:92-97, 2021, DOI: 10.1016/j.nucmedbio.2021.01.004

​【学会発表】

  1. 中村吉伸,中西猛夫,プロスタグランジン膜輸送体SLCO2A1による海馬PGD2濃度調節,日本薬学会第141年会(広島),オンライン,3/26-29,2021

  2. 中西猛夫,中村吉伸,シュンバ・メロディ,タバコ煙抽出物がプロスタグランジン膜輸送体(SLCO2A1)に及ぼす影響,日本薬学会第141年会(広島),オンライン,3/26-29,2021

2020 (from Jan. to Dec.)

​【論文】

  1. Liu W, Nakano M, Nakanishi T, Nakajima M, Tamai I., Post-transcriptional regulation of OATP2B1 transporter by a microRNA, miR-24, Drug Metab Pharmacokinet, 35:515-521, 2020, DOI: 10.1016/j.dmpk.2020.07.007

  2. Kobayashi M, Mizutani A, Nishi K, Muranaka Y, Nishii R, Shikano N, Nakanishi T, Tamai I, Kleinerman ES, Kawai K., [131I]MIBG exports via MRP transporters and inhibition of the MRP transporters improves accumulation of [131I]MIBG in neuroblastoma, Nucl Med Biol, 90-91:49-54, 2020, DOI:10.1016/j.nucmedbio.2020.09.004

  3. Nakanishi T, Sakiyama S, Takashima H, Honda R, Shumba MN, Nakamura Y, Kasahara K, Tamai I., Toxicological implication of prostaglandin transporter SLCO2A1 inhibition by cigarette smoke in exacerbation of lung inflammation, Toxicol Appl Pharmacol, 405:115201, 2020, DOI: 10.1016/j.taap.2020.115201.

  4. Shimada H, Hashimoto R, Aoki A, Yamada S, Oba KI, Kawase A, Nakanishi T, Iwaki M.,The regulatory mechanism involved in the prostaglandin E2 disposition in carbon tetrachloride-induced liver injury, Prostaglandins Leukot Essent Fatty Acids, 155:102081, 2020, DOI: 10.1016/j.plefa.2020.102081

  5. Inagaki M, Nishimura T, Nakanishi T, Shimada H, Noguchi S, Akanuma SI, Tachikawa M, Hosoya KI, Tamai I, Nakashima E, Tomi M., Contribution of prostaglandin transporter OATP2A1/SLCO2A1 to placenta-to-maternal hormone signaling and labor induction, iScience, 23:101098, 2020, DOI: 10.1016/j.isci.2020.101098

  6. Nakata R, Nakamura Y, Hosomi S, Okuda H, Nishida Y, Sugita N, Itani S, Nadatani Y, Otani K, Tanaka F, Kamata N, Taira K, Nagami Y, Tanigawa T, Watanabe T, Yamagami H, Nakanishi T, Fujiwara Y: Slco2a1 deficiency exacerbates experimental colitis via inflammasome activation in macrophages: a possible mechanism of chronic enteropathy associated with SLCO2A1 gene, Sci Rep, 10:4883, 2020, DOI: 10.1038/s41598-020-61775-9.

  7. Hirayama M, Hoshino Y, Yoshii K, Toda R, Kawabata Y, Nakanishi T, Tamai I., Identification of the uptake transporter responsible for distribution of acotiamide into stomach tissue, Mol Pharm, 17:1071-1078, 2020, DOI: 10.1021/acs.molpharmaceut.9b00894

  8. Kobayashi M, Nishi K, Mizutani A, Okudaira H, Nakanishi T, Shikano N, Nishii R, Tamai I, Kawai K: Transport mechanism and affinity of [99mTc]mercaptoacetyltriglycine ([99mTc]MAG3) on the apical membrane of renal proximal tubule cells, Nucl Med Biol, 84-85:33-37, 2020, DOI: 10.1016/j.nucmedbio.2020.01.002

  9. Saveleva EE, Tyutrina ES, Nakanishi T, Tamai I, Salmina AB., ИНГИБИТОРЫ НАТРИЙ-ЗАВИСИМОГО ПЕРЕНОСЧИКА ЖЕЛЧНЫХ КИСЛОТ (ASBT) КАК ПЕРСПЕКТИВНЫЕ КАРСТВЕННЫЕ СРЕДСТВА, Biomed Khim, 66, 185-195, 2020 DOI: 10.18097/PBMC20206603185 (Article in Russian)(総説)

​【学会発表】

  1. 中村吉伸,中西猛夫:SLCO2A1 による脳の領域特異的なプロスタグランジン D2 動態制御機構,第35回日本薬物動態学会年会,オンライン,12/1,2020

  2. メロディ N. シュンバ, 中村吉伸, 中西猛夫:Effect of cigarette smoke extract on the function and expression of transporter SLCO2A1, 第5回トランスポーター研究会関東部会,オンライン,11/24,2020

  3. 中村吉伸,坂口貴俊,中西猛夫:プロスタグランジン膜輸送体SLCO2A1による中枢神経系におけるPGD2濃度調節機構, 第15回トランスポーター研究会年会,オンライン, 10/12-16, 2020

  4. 森田真也, 中村吉伸, 辻徳治, 寺田智祐, ABCB4の糖鎖修飾がリン脂質排出機能に与える影響, 第15回トランスポーター研究会年会, オンライン, 10/12-16,2020