top of page
透明なグラデーションセンター

Publication List for Original Articles and Reviews 

​​

  1. Nakanishi T, Kawasaki Y, Nakamura Y, Kimura Y, Kawamura K, Shumba NM, Shimokawa N, An implication of the mitochondrial carrier SLC25A3 as an oxidative stress modulator in NAFLD, Exprimental Cell Research, 431:113740, 2023. DOI: 10.1016/j.yexcr.2023.113740

  2. Nakamura Y, Aizawa C, Kawata H, Nakanishi T, N-glycosylation modifies prostaglandin E2 uptake by reducing cell surface expression of SLCO2A1, Prostaglandins Other Lipid Mediat, 165:106714, 2023. DOI: 10.1016/j.prostaglandins.2023.106714

  3. Sato K, Mizutani A, Muranaka Y, Yao J, Kobayashi M, Yamazaki K, Nishii R, Nishi K, Nakanishi T, Tamai I, Kawai K: Biological Distribution after Oral Administration of Radioiodine-Labeled Acetaminophen to Estimate Gastrointestinal Absorption Function via OATPs, OATs, and/or MRPs, Pharmaceutics, 15(2):497, 2023, DOI: 10.3390/pharmaceutics15020497. (Open Access)

  4. Sato K, Seki T, Mizutani A, Muranaka Y, Hirota S, Nishi K, Yamazaki K, Nishii R, Nakanishi T, Tamai I, Kawai K, Kobayashi M: A single high-dose irradiation changes accumulation of methotrexate and gene expression levels of SLC and ABC transporters in cancer cells, Front Pharmacol, 13, 1069321, 2023, DOI: 10.3389/fphar.2022.1069321. (Open Access)

  5. ​Nakamura Y, Kozakai H, Nishio T, Yoshida K, Nakanishi T, Phenolsulfonphthalein as a surrogate substrate to assess altered function of the prostaglandin transporter SLCO2A1, Drug Metab Pharmacokinet, 44, 100452, 2022, DOI: 10.1016/j.dmpk.2022.100452

  6. Kobayashi M, Mizutani A, Muranaka Y, Nishi K, Komori H, Nishii R, Shikano N, Nakanishi T, Tamai I, Kawai K., Biological Distribution of Orally Administered [123I]MIBG for Estimating Gastrointestinal Tract Absorption, Pharmaceutics, 14, 61, 2021, DOI: 10.3390/pharmaceutics14010061 (Open Access)

  7. Komori H, Fujita D, Shirasaki Y, Zhu Q, Iwamoto Y, Nakanishi T, Nakajima M, Tamai I., MicroRNAs in apple-derived nanoparticles modulate intestinal expression of OATP2B1/SLCO2B1 in Caco-2 cells, Drug Metab Dispos, 49, 803-809, 2021, DOI: 10.1124/dmd.121.000380 

  8. Kobayashi M, Mizutani A, Okamoto T, Muranaka Y, Nishi K, Nishii R, Shikano N, Nakanishi T, Tamai I, Kleinerman ES, Kawai K., Assessment of drug transporters involved in the urinary secretion of [99mTc]dimercaptosuccinic acid. Nucl Med Biol. 94-95:92-97, 2021, DOI: 10.1016/j.nucmedbio.2021.01.004 ​

  9. Saveleva EE, Tyutrina ES, Nakanishi T, Tamai I, Salmina AB., The inhibitors of the apical sodium-dependent bile acid transporter (ASBT) as promising drugs, Biochem Mosc Suppl B Biomed Chem, 15:16-26, 2021, DOI: 10.1134/S1990750821010078【REVIEW】

  10. Nakanishi T, Nakamura Y, Umeno J., Recent advances in studies of SLCO2A1 as a key regulator of the delivery of prostaglandins to their sites of action, Pharmacol Ther, 223:107803, 2021, DOI : 10.1016/j.pharmthera.2021.107803【REVIEW】

  11. Saveleva EE, Tyutrina ES, Nakanishi T, Tamai I, Salmina AB., ИНГИБИТОРЫ НАТРИЙ-ЗАВИСИМОГО ПЕРЕНОСЧИКА ЖЕЛЧНЫХ КИСЛОТ (ASBT) КАК ПЕРСПЕКТИВНЫЕ КАРСТВЕННЫЕ СРЕДСТВА, Biomed Khim, 66, 185-195, 2020 DOI: 10.18097/PBMC20206603185 (Article in Russian)【REVIEW】

  12. Kobayashi M, Nishi K, Mizutani A, Okudaira H, Nakanishi T, Shikano N, Nishii R, Tamai I, Kawai K: Transport mechanism and affinity of [99mTc]mercaptoacetyltriglycine ([99mTc]MAG3) on the apical membrane of renal proximal tubule cells, Nucl Med Biol, 84-85:33-37, 2020, DOI: 10.1016/j.nucmedbio.2020.01.002 

  13. Hirayama M, Hoshino Y, Yoshii K, Toda R, Kawabata Y, Nakanishi T, Tamai I., Identification of the uptake transporter responsible for distribution of acotiamide into stomach tissue, Mol Pharm, 17:1071-1078, 2020, DOI: 10.1021/acs.molpharmaceut.9b00894 

  14. Nakata R, Nakamura Y, Hosomi S, Okuda H, Nishida Y, Sugita N, Itani S, Nadatani Y, Otani K, Tanaka F, Kamata N, Taira K, Nagami Y, Tanigawa T, Watanabe T, Yamagami H, Nakanishi T, Fujiwara Y: Slco2a1 deficiency exacerbates experimental colitis via inflammasome activation in macrophages: a possible mechanism of chronic enteropathy associated with SLCO2A1 gene, Sci Rep, 10:4883, 2020, DOI: 10.1038/s41598-020-61775-9 (Open Access) 

  15. Inagaki M, Nishimura T, Nakanishi T, Shimada H, Noguchi S, Akanuma SI, Tachikawa M, Hosoya KI, Tamai I, Nakashima E, Tomi M., Contribution of prostaglandin transporter OATP2A1/SLCO2A1 to placenta-to-maternal hormone signaling and labor induction, iScience, 23:101098, 2020, DOI: 10.1016/j.isci.2020.101098 (Open Access) 

  16. Shimada H, Hashimoto R, Aoki A, Yamada S, Oba KI, Kawase A, Nakanishi T, Iwaki M.,The regulatory mechanism involved in the prostaglandin E2 disposition in carbon tetrachloride-induced liver injury, Prostaglandins Leukot Essent Fatty Acids, 155:102081, 2020, DOI: 10.1016/j.plefa.2020.102081 

  17. Nakanishi T, Sakiyama S, Takashima H, Honda R, Shumba MN, Nakamura Y, Kasahara K, Tamai I., Toxicological implication of prostaglandin transporter SLCO2A1 inhibition by cigarette smoke in exacerbation of lung inflammation, Toxicol Appl Pharmacol, 405:115201, 2020, DOI: 10.1016/j.taap.2020.115201 

  18. Kobayashi M, Mizutani A, Nishi K, Muranaka Y, Nishii R, Shikano N, Nakanishi T, Tamai I, Kleinerman ES, Kawai K., [131I]MIBG exports via MRP transporters and inhibition of the MRP transporters improves accumulation of [131I]MIBG in neuroblastoma, Nucl Med Biol, 90-91:49-54, 2020, DOI:10.1016/j.nucmedbio.2020.09.004

  19. Liu W, Nakano M, Nakanishi T, Nakajima M, Tamai I., Post-transcriptional regulation of OATP2B1 transporter by a microRNA, miR-24, Drug Metab Pharmacokinet, 35:515-521, 2020, DOI:10.1016/j.dmpk.2020.07.00 

  20. Kobayashi M, Nishi K, Mizutani A, Hokama T, Matsue M, Tsujikawa T, Nakanishi T, Nishii R, Tamai I, Kawai K: Imaging of hepatic drug transporters with [131I]6-β-iodomethyl-19-norcholesterol, Sci Rep, 9:13413, 2019, DOI: 10.1038/s41598-019-50049-8

  21. Nakamura Y, Sakaguchi T, Tamai I, Nakanishi T, Quantification of prostaglandin E2 concentration in interstitial fluid from the hypothalamic region of free-moving mice, Bio Protoc, 9: e3324, 2019, DOI: 10.21769/BioProtoc.3324

  22. Arakawa H, Kubo H, Washio I, Staub AY, Nedachi S, Ishiguro N, Nakanishi T, Tamai I: Rat kidney slices for evaluation of apical membrane transporters in proximal tubular cells, J Pharm Sci, 108:2798-2804, 2019, DOI: 10.1016/j.xphs.2019.03.031

  23. Nishizawa K, Yoda N, Morokado F, Komori H, Nakanishi T, Tamai I: Changes of drug pharmacokinetics mediated by downregulation of kidney organic cation transporters Mate1 and Oct2 in a rat model of hyperuricemia, PLoS One, 14:e0214862, 2019, DOI: 10.1371/journal.pone.0214862

  24. Arakawa H, Amezawa N, Katsuyama T, Nakanishi T, Tamai I: Uric acid analogue as a possible xenobiotic marker of uric acid transporter Urat1 in rats, Drug Metab Pharmacokinet, 34:155-158, 2019, DOI: 10.1016/j.dmpk.2018.12.003

  25. Washio I, Nakanishi T, Ishiguro N, Bister B, Tamai I: Effect of endogenous multidrug resistance 1 and P-glycoprotein expression on anticancer drug resistance in colon cancer cell lines, Biopharm Drug Dispos, 40:32-43, 2019, DOI: 10.1002/bdd.2167

  26. Myint K, Biswas R, Li Y, Jong N, Jamieson S, Liu J, Han C, Squire C, Merien F, Lu J, Nakanishi T, Tamai I, McKeage M: Identification of MRP2 as a targetable factor limiting oxaliplatin accumulation and response in gastrointestinal cancer, Sci Rep, 9:2245, 2019, DOI: 10.1038/s41598-019-38667-8 (Open Access)

  27. ​Nakanishi T, Takashima H, Uetoko Y, Komori H, Tamai I: Experimental evidence for re-secretion of PGE2 across rat alveolar epithelium by OATP2A1/SLCO2A1-mediated transcellular transport, J Pharmacol Exp Ther, 368:317-325, 2019, DOI: 10.1124/jpet.118.249789​

bottom of page